{
  lib,
  stdenv,
  substituteAll,
  buildPythonPackage,
  fetchPypi,
  pythonOlder,
  asn1crypto,
  cffi,
  cryptography,
  pkgconfig, # see nativeBuildInputs
  pkg-config, # see nativeBuildInputs
  pytestCheckHook,
  pyyaml,
  setuptools-scm,
  tpm2-tss,
  tpm2-tools,
  swtpm,
}:

let
  isCross = (stdenv.buildPlatform != stdenv.hostPlatform);
in
buildPythonPackage rec {
  pname = "tpm2-pytss";
  version = "2.2.1";
  format = "setuptools";

  disabled = pythonOlder "3.7";

  src = fetchPypi {
    inherit pname version;
    hash = "sha256-uPFUc0IvN39ZxyF9zRR5FlzOYt+jOTTsl2oni68unv4=";
  };

  patches =
    [
      # Fix hardcoded `fapi-config.json` configuration path
      ./fapi-config.patch
      # Backport for https://github.com/tpm2-software/tpm2-pytss/pull/576
      # This is likely to be dropped with the next major release (>= 2.3)
      ./pr576-backport.patch
    ]
    ++ lib.optionals isCross [
      # pytss will regenerate files from headers of tpm2-tss.
      # Those headers are fed through a compiler via pycparser. pycparser expects `cpp`
      # to be in the path.
      # This is put in the path via stdenv when not cross-compiling, but this is absent
      # when cross-compiling is turned on.
      # This patch changes the call to pycparser.preprocess_file to provide the name
      # of the cross-compiling cpp
      (substituteAll {
        src = ./cross.patch;
        crossPrefix = stdenv.hostPlatform.config;
      })
    ];

  postPatch = ''
    sed -i "s#@TPM2_TSS@#${tpm2-tss.out}#" src/tpm2_pytss/FAPI.py
  '';

  # Hardening has to be disabled
  # due to pycparsing handling it poorly.
  # See https://github.com/NixOS/nixpkgs/issues/252023
  # for more details.
  hardeningDisable = [ "fortify" ];

  nativeBuildInputs = [
    cffi
    pkgconfig # this is the Python module
    pkg-config # this is the actual pkg-config tool
    setuptools-scm
  ];

  buildInputs = [ tpm2-tss ];

  propagatedBuildInputs = [
    cffi
    asn1crypto
    cryptography
    pyyaml
  ];

  doCheck = true;

  nativeCheckInputs = [
    pytestCheckHook
    tpm2-tools
    swtpm
  ];

  pythonImportsCheck = [ "tpm2_pytss" ];

  meta = with lib; {
    homepage = "https://github.com/tpm2-software/tpm2-pytss";
    changelog = "https://github.com/tpm2-software/tpm2-pytss/blob/${version}/CHANGELOG.md";
    description = "TPM2 TSS Python bindings for Enhanced System API (ESYS)";
    license = licenses.bsd2;
    maintainers = with maintainers; [ baloo ];
  };
}